Welcome to Namasivayam Group
PUBLICATIONS
Recent Publications
Total Citations (as of 01 February 2026): 2932
h-Index: 34; i-10 index: 72
*Corresponding author
126. Biomass-Derived Coriander Carbon Quantum Dots for Oxidative Stress Mitigation and Nanoscale Imaging in Plants. M.Kumar, B.B.Shrestha, C.Shanmugavel, T.Fujiwara, E.Sivaniah, and Ganesh N.Pandian*. 2026, Plant Nano Biology, 15, 100236.
125. Sustainable carbon nanodots from medicinal plants: Unlocking their biomedical and theranostic applications. Harish G.S., M. Amrish,
D. Ramaraj, S. Kunjiappan, Ganesh N.Pandian, S. Chockalingam, G. Packirisamy. 2026, Ind. Crops. Prod., 240, 122600.
124. Scaling up nanobiosensors for commercialization purposes” in a book titled “Nanobiosensors Technology: From Theory to Practice (Micro and Nano Technologies) ” Omal Surya Souraph S, Damini Verma, Nabeel Ahmad, Ganesh N. Pandian, Gopinath Packirisamy. Elsevier. (2026)
123. Twist, Grind, Translocate: Pepper-Mill Dynamics of MSPA protein pore during ssDNA Transport.
P.Dey, B. Meza-Gonzalez, Ganesh N Pandian, D. Packwood, Phys Chem Chem Phys-PCCP, 2026. 28, 4900-4908.
122. Chalcones as versatile probes for metal ion detection in a book titled “Chalcones and their Derivatives: From Synthesis to Applications.” P.A.Matthew, G.R.Tharani, K.Dhanavardhini, C.Shanmugavel, Ganesh.N.Pandian, and R.Mangaiyarkarasi.
Elsevier, (2026), Chapter 21, 581-610, ISBN: 978-0-443-30122-3. (10.1016/B978-0-443-30122-3.00004-2).
121. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications in a book titled
“Chalcones and their Derivatives: From Synthesis to Applications.” M.Shwetha, J.Atchaya, C.Shanmugavel,
Ganesh.N.Pandian, S.Karthikeyan. Elsevier, (2026), Chapter 23, 633-658, ISBN: 978-0-443-30122-3.
(10.1016/B978-0-443-30122-3.00002-9).
2025
120. Targeted Delivery of Bezafibrate via Silica Nanoparticles Restores Mitochondrial Function and Reduces Oxidative Stress in Insulin-Resistant Cells. A.Jannat, S.Chinnathambi, G.Packirisamy, L.B.Shano, S.Karthikeyan, R.Mangaiyarkarasi, Y.Taniguchi, and G. N. Pandian*.
ACS Applied Bio Materials, 2025, 8 (10), 8687-8707
119. Regulation of liquid-liquid phase separation using butterfly-shaped gold nanoparticles
T. Nobeyama and Ganesh N. Pandian*, Precision Medicine, Vol.8, No.7, 2025, pp 74-79
118. Examining Sleep Signals at the Cradle of Life: Can phylogenomic analysis of the Last Universal Common Ancestor (LUCA) reveal the fundamental role of sleep?
S. R Pandi-Perumal, K. M. Saravanan, D. W. Spence, S. Paul, Ganesh N. Pandian*, S. B. Chidambaram. doi: https://doi.org/10.1101/2025.03.21.644522
117. Structural Impact of Anthracene-Appended Mn-MOFs on Human Serum Albumin and Their Cellular Implications.
S. Chinnathambi, M. Kumar, B. Dutta, S. Karthikeyan, K. Saravanan, S. Kmiecik, V. Thangavel, and G. N. Pandian*.
ACS Applied Bio Materials, (2025). 8 (7), 6397-6414
116. Tiny but Mighty! N, N-dimethyl-4-(5-nitrothiophen-2-yl)aniline, a Push-Pull Fluorescent Dye for Lipid Droplet Imaging.
W.A. Wee, T.M. Andini, T. Kumagai, S. Chinnathambi, Ganesh N. Pandian, A. Millius, H. Sugiyama, D.M. Standley, and S. Park. 2025,
Anal. Chim. Acta, 1359, 344130
115. Bio-inspired Nitrogen-Doped Carbon Quantum Dots: A Green Route for Bioimaging and Nano-biosensing.
M.Kumar, B.B. Shrestha, S. Chinnathambi, B. Dutta, E. Sivaniah, and Ganesh N. Pandian*. 2025, Ind. Crops. Prod., 227, 120817.
114. Fluorescence-based point-of-care nano biosensors for the detection of cardiovascular disease biomarkers, K.Dhanavardhini, P.A.Matthew, G.R. Tharani, C.Ahuja, K. Subramani, S. Chinnathambi, G.N. Pandian, A.N. Grace, R. Mangaiyarkarasi, in a book titled “Point-of-Care Technology for Portable Testing Devices.” Academic Press, (2025), 185-213. ISBN: 978-0-443-33030-8. (10.1016/B978-0-443-33030-8.00006-8).
113. Doxorubicin-Conjugated Terbium-Doped Carbon Dots for Site-Specific Colon Cancer Theranostics.
K.Dhanavardhini, A.Sagayaraj, P.Matthew, T.Dasgupta, G R, Tharani, R.Tamizhselvi, S.Anandh, N.Nireekshana, K.Udayakumar, K.Venkat S, S.Karthikeyan, S.Chinnathambi, Ganesh N. Pandian, A.Nirmala Grace, C.C. Sangeetha, R.Mangaiyarkarasi. 2025
ACS Appl. Nano Mater. 8, 13, 6274-6287.
2024
112. Subcutaneous adipose tissue: Implications in dermatological diseases and beyond
R. Ziadlou, Ganesh N Pandian, J. Hafner, C. Akdis, G. Stingl, E. Maverakis, M-C Brüggen, 2024, Allergy, 79, 3310-3325
111. Nucleic acid-based small molecules as targeted transcription therapeutics for immunoregulation
D. Bai, R. Ziadlou, T. Vaijayanthi, S. Karthikeyan, S. Chinnathambi, A. Parthasarathy. L. Cai, M-C. Bruggen.
H. Sugiyama* and Ganesh N. Pandian.* 2024, Allergy, 79, 843-860.
110. Design and Integration of IoRT-Enabled Robotic Systems with Wearable Devices in a Digital Twin Framework
C. Rajurkar, B. Murugan and Ganesh N. Pandian.* 2024, IEEE, pp. 45-49, doi: 10.1109/ICCRE61448.2024.10589845.
109. Creation of metal complex-integrated tensegrity triangle DNA crystals. K.Abe, H.Eki, Y.Hirose, S.Park, S.Chinnathambi,
Ganesh N. Pandian, K.Takeda, H.Sugiyama, M.Endo. 2024, Molecules, 29, 4674.
108. MOFs for Next-Generation Cancer Therapeutics through a Biophysical Approach - A Review. L.B.Shanoa, L.J.Kennedy,
S.Karthikeyan, S.Chinnathambi, Ganesh N. Pandian. 2024, Frontiers in Bioengineering and Biotechnology, 12,1397804.
107. Clock-Sleep Communication. S. R. Pandi-Perumal, K. M. Saravanan, S. Paul, Ganesh N. Pandian, S. Chidambaram. 2024,
Current Mol. Med., DOI: 10.2174/0115665240305615240630113434
106. Molecular design for cardiac cell differentiation using a small dataset and decorated shape features
F. Etezadi, S. Ito, K. Yasui, R. K.Abdalkader, I.Minami, M. Uesugi, Ganesh N Pandian, H. Nakano, A.i Nakano, D. M. Packwood,
2024, J. Chem. Inf. Model., 64 (23) 8824–8837.
105. Surface charge-dependent cytokine production using near-infrared emitting silicon quantum dots.
S.Chinnathambi, N.Shirahata, P.Lesani, V.Thangavel and Ganesh N. Pandian*, 2024, Sci. Rep., 14, 9618.
104. Biomass-derived carbon dots as fluorescent quantum probes to visualize and modulate inflammation.
M.Kumar, S. Chinnathambi, N.M.Bakhori, N.Abu, F. Etezadi, V.Thangavel, D.Packwood, E.Sivanaiah and Ganesh N. Pandian*,
2024, Sci. Rep., 14,12665
103. Chalcone derivatives interaction with human serum albumin and cyclooxygenase-2
S. Karthikeyan, S. Chinnathambi, A. Thirunarayanan, L.B. Shano, H. Arasappan, S. Anandh; R. Mangaiyarkarasi, N. Abu, S. Ganesan,
Ganesh N. Pandian.* 2024, RSC Adv., 14, 2835-2849.
102. Waking up the sleep field: An overview of the implications of genetics and bioinformatics of sleep
S. R. Pandi-Perumal, K. M. Saravanan, S. Paul, Ganesh N. Pandian, S. Chidambaram. 2024, Mol. Biotechnol., 66(5), 919-931
101. An ultra-sensitive detection of melamine in milk using rare earth doped graphene quantum dots-synthesis and optical spectroscopic approach
F. Anjila, GR Tharani, A. Sundaramoorthy, V. K. Shanmugam, K. Subramani, S. Chinnathambi, Ganesh N Pandian, V. Raghavan, A.N. Grace, S. Ganesan, M.Rajendiran, 2024, Microchem. J., 196, 109670.
2023
100. Bat-Associated Microbes: Opportunities and Perils, An Overview.
J. Dhivahar, A. Parthasarathy, E. Lavanya, B. Kovi, Ganesh N. Pandian*, 2023, Heliyon, e22351
N. Abu, S. Chinnathambi, M. Kumar, F. Etezadi; M. B. Noremylia, A. Zubir, N. M. Salleh, Shueb, R. Hanim, K. Subramani; T. Vaijayanthi,
A. Jaafar; Ganesh N. Pandian*, 2023, RSC Adv., 13(40): 28230–28249.
98. Pyrrole-Imidazole Polyamide–A Front Runner in Mid-Molecular Pharmaceuticals
T. Vaijayanthi, Ganesh N. Pandian*, H. Sugiyama*, 2023, TCI MAIL., 193, 2-15 https://www.tcichemicals.com/assets/cms-pdfs/193Eall.pdf.
97. DNA methylation modification patterns identify prognosis responses to immunotherapy and targeted therapy
D. Bai, Y. Cheng, X. Lu, Ganesh N Pandian, H. Sugiyama, 2023, Front. Biosci. - Landmark, 28(9), 224.
96. Pyrrole-Imidazole Polyamides - A Frontrunner in Nucleic Acid-based Small Molecule Drugs
T. Vaijayanthi, Ganesh N. Pandian*, H. Sugiyama*, 2023, Adv. Ther., 6, 2300022. https://doi.org/10.1002/adtp.202300022
S. Chinnathambi, N. Shirahata, M. Kumar, S. Karthikeyan, K. Abe, V. Thangavel and Ganesh N. Pandian*, 2023, RSC Adv., 13 (9), 6051-6064.
94. Nanoparticle-Based Artificial Mitochondrial DNA Transcription Regulator: MitoScript
L. Yang, C. Rathnam, T. Hidaka, Y. Hou, B. Conklin, Ganesh N Pandian, H. Sugiyama, K-B Lee, 2023, Nano Lett., 23 (5), 2046-2055.
[FRONT COVER]
93. Identification of genes responsible for the social skill in the earthworm, Eudrilus eugeniae
S. Lathakumari, S. Seenipandian, S. Balakrishnan, A. Preena, Ganesh N Pandian, H. Sugiyama. S. Sivasubramaniam, 2023,
Gene Rep., 31, 101774.
92. A Biophysical Approach of tyrphostin AG879 Binding Information in: Bovine Serum Albumin, Human ErbB2, c-RAF1 Kinase, SARS-CoV-2 main protease and Angiotensin-Converting Enzyme 2 Drugs
S. Karthikeyan, A. Sundaramoorthy, S. Kandasamy, G. Bharanidharan, P. Aruna, R. Suganya, R. Mangaiyarkarasi, S. Ganesan, Ganesh N. Pandian, A. Ramamoorthi, S. Chinnathambi, 2023, J. Biomol. Struct. Dyn., In press.
S. Karthikeyan, M. Grishinab, S. Kandasamy, R. Mangaiyarkarasi, A. Ramamoorthi, S. Chinnathambi, Ganesh N. Pandian, L.J. Kennedy
2023, J. Biomol. Struct. Dyn., 42(3), 1455-1468.
90. Sequence-specific chromosomal DNA binders: An unfulfilled promise
Z. Yu, Ganesh N. Pandian*, H. Sugiyama*, 2023, In Nucleic Acids in Medicinal Chemistry and Chemical Biology, (eds L. Zhang, X. Tang, Z. Xi and J. Chattopadhyaya). https://doi.org/10.1002/9781119692799.ch5 Wiley press.
89. Mitochondria and G-quadruplex Evolution: An Intertwined Relationship
V. J. Sahayasheela, Z. Yu, T. Hidaka, Ganesh N. Pandian, H. Sugiyama, 2023, Trends in Genetics, 39, 15-30
88. Food Intake and Colorectal Cancer
A. Kumar, S. Chinnathambi, M. Kumar & Ganesh N. Pandian
2023, Nutrition and Cancer, 75(9), 1710-1742.
2022
87. Machine learning approach to ophthalmological circadian therapeutics from retina transcriptome dataset.
D. Sahu, S. Ramasamy, G. R. Sahu, S.Sharma, A. Ghosh, S. Sethu, D.Packwood, Ganesh N. Pandian, Perspectives on Artificial Intelligence and Machine Learning in Materials Science, (2022) 55-60
86. Artificial genetic switches and DNA origami: Current landscape and prospects as designer therapeutics and visualization tools
Ganesh N. Pandian*, S. Mishra, H. Sugiyama*, 2022, In: Sugimoto, N. (eds) Handbook of Chemical Biology of Nucleic Acids. Springer, Singapore. https://doi.org/10.1007/978-981-16-1313-5_64-1
85. Artificial intelligence in microbial natural product drug discovery: Current and emerging role
V. J. Sahayasheela, M.B. Lankadasari, V.M. Dan, S. Dastager, Ganesh N. Pandian*, H. Sugiyama*, 2022, Nat. Prod. Rep., 39, 2215-2230 (FRONT COVER)
84. Structural colour enhanced microfluidics
D. Qin, A. H. Gibbons, M.M. Ito, S. Sangamithirai Parimalam, H. Jiang, H.E. Karahan, B. Ghalei, D. Yamaguchi, Ganesh N. Pandian, and E. Sivaniah, 2022, Nature Communications 13: 2282
83. Chemical probe-based Nanopore Sequencing to Selectively Assess the RNA modifications.
S. Ramasamy, V.J. Sahayasheela, Z. Yu, T. Hidaka, L. Cai, H. Sugiyama* and Ganesh N. Pandian*, 2022, ACS Chem. Biol. 17, 2704–2709.
82. An informatics approach to distinguish RNA modifications in nanopore direct RNA sequencing .
S. Ramasamy, S. Mishra, S. Sharma, S. Sangamithirai Parimalam, V. Thangavel, Y. Fujita, B. Kovi, H. Sugiyama* and Ganesh N. Pandian*, 2022, Genomics 114, 110372
81. Targeted epigenetic induction of mitochondrial biogenesis enhances antitumor immunity in mouse model.
M. Malinee, Ganesh N. Pandian* and H. Sugiyama*. 2022, CELL Chem. Biol. 29 (3): 463-475. e6 (Highlighted in 日刊工業新聞; 京都新聞; 日本経済新聞; 東京新聞; 科学新聞; GEN EN News `Cancer Immunotherapy Gets a Power Up by PIP`, Sept 14-16, 2021).
80. Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation.
T. Hidaka, K. Hashiya, T. Bando, Ganesh N. Pandian* and H. Sugiyama*. 2022, CELL Chem. Biol. 29 (4): 690-695. e5 (Highlighted in テレビ大阪ニュース https://youtu.be/jZnr_YwuiGo, Biospectrum asia news `Japan suggests DNA deletion to treat mitochondrial diseases`. Aug 30, 2021
79. Inhibition of GLI-mediated transcription by cyclic pyrrole-imidazole polyamide in cancer stem cells.
V.J. Sahayasheela, Z. Yu, Y. Hirose, Ganesh N. Pandian*, T. Bando and H. Sugiyama* . 2022, Bull. Chem. Soc. J. 95 (4): 693-699.
78. Comparative analysis of mitochondrial genomes in different species reveals the evolution of G-quadruplexes.
V.J. Sahayasheela, Z. Yu, Ganesh N. Pandian* and H. Sugiyama* . ResearchSquare Pre-print https://doi.org/10.21203/rs.3.rs-1126357/v1
77. A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1
R.Manoharan, S.Karthikeyan, S.Anandh, S.Ramireddy, G.Bharanidharan, P.Aruna, R.Mangaiyarkarasi, S.Chinnathambi, Ganesh N. Pandian, S.Ganesan., 2022, Results in Chemistry, 5, p100755.
76. Facile Synthesis of Hafnium Oxide Nanoparticle Decorated on Graphene Nanosheet and Its Photocatalytic Degradation of Organic Pollutants under UV-Light Irradiation
V. Jayaraman, S. Mahalingam, S. Chinnathambi, Ganesh N. Pandian, A. Prakasarao, Sa. Ganesan, J. Ramasamy, S. Ayyaru and Y. Ahn, 2022, Appl. Sci. 12, 11222: https://doi.org/10.3390/app122111222
75. Classification of COVID-19 from chest x-ray images using deep features and correlation coefficient.
R. Kumar, R. Arora, V. Bansal, V. J. Sahayasheela, H.Buckchash, J. Imran, N. Narayanan, Ganesh N Pandian*, B. Raman. 2022, Multimed Tools Appl. 2022, https://doi.org/10.1007/s11042-022-12500-3.
74. Scientists Against War: A Plea to World Leaders for Better Governance.
S.R. Pandi-Perumal, V. M. Kumar, V.M., Ganesh N Pandian* . 2022, Sleep Vigilance. https://doi.org/10.1007/s41782-022-00198-0.
~2021
73. 核移行性が改良されたピロール－イミダゾールポリアミド.
T. Hidaka, Ganesh N. Pandian and H. Sugiyama 2021, PCT/JP2021/031757 .
京大整理番号：7068
72. Sequence-specific control of mitochondrial gene transcription using programmable synthetic gene switches called MITO-PIPs.
T. Hidaka, H. Sugiyama and Ganesh N. Pandian*. 2021, Methods in Molecular Biology (Clifton, N.J.), 2275, 217-225.
In: Weissig V., Edeas M. (eds) Mitochondrial Medicine. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1262-0_13
71. Designing biomimicking synthetic transcription factors for therapeutic gene modulation.
Ganesh N. Pandian* and H. Sugiyama*. 2021, In: Wang D.O., Packwood D. (eds) Cell-Inspired Materials and Engineering. Fundamental Biomedical Technologies. pp 135–161. Springer, Cham. https://doi.org/10.1007/978-3-030-55924-3_6
70. AI-based Diagnosis of COVID-19 Patients Using X-ray Scans with Stochastic Ensemble of CNNs
R. Arora, V. Bansal, H.Buckchash, R. Kumar, V. J. Sahayasheela, N. Narayanan, Ganesh N Pandian, B. Raman, 2021, Phys. Eng. Sci. Med, 1-15
69. Targeted epigenetic modulation using a DNA-based histone deacetylase inhibitor enhances cardiomyogenesis in mouse embryonic stem cells.
J-A. Lee, J. Taniguchi, G. Kashiwazaki, Ganesh N. Pandian, N. Praveen, H. Sugiyama, D. De, K.K. Kim. 2021, J. Cell. Physiol. 236:3946–3962.
68. A Near-Infrared Fluorogenic Pyrrole–Imidazole Polyamide Probe for Live-Cell Imaging of Telomeres
Y. Tsubono, Y. Kawamoto, T. Hidaka, Ganesh N. Pandian*, K. Hashiya, T. Bando, and H. Sugiyama*. 2020, J. Am. Chem. Soc. 142, 41, 17356–17363
67. Accurate Prediction of COVID-19 using Chest X-Ray Images through Deep Feature Learning model with SMOTE and Machine Learning Classifiers.
R. Kumar, R. Arora, V. Bansal, V. J. Sahayasheela, H.Buckchash, J. Imran, N. Narayanan, Ganesh N Pandian*, B. Raman, 2020, medRxiv, https://doi.org/10.1101/2020.04.13.20063461
66. Enhanced nuclear accumulation of pyrrole–imidazole polyamides by incorporation of the tri-arginine vector.
T. Hidaka, Y. Tsubono, K. Hashiya, T. Bando, Ganesh N. Pandian and H. Sugiyama. 2020, Chem. Commun. 56, 12371 – 12374.
65. Differentially expressed genes on the growth of mouse Leydig cells treated with standardised Eurycoma longifolia extract
K.B. Yun, S. Lim, H. Sugiyama, Ganesh N. Pandian and K.L. Chan. 2020, Mol. Med. Rep., 22, 3645 – 3658.
64. Discovery of 3-(Benzofuran-2-ylmethyl)-1H-Indole derivatives as potential autophagy inducers in cervical cancer cells.
S. K. Siddiqui, V.J. Sahayasheela, S. Kolluru, Ganesh N. Pandian, T.R. Santhoshkumar, V.P.Dan, C.V. Ramana. 2020, Bioorg. Med. Chem.30, 127431.
63. CGHF: A Computational Decision Support System for Glioma Classification Using Hybrid Radiomics-and Stationary Wavelet-Based Features
R. Kumar, A. Gupta, H.S. Arora, Ganesh N. Pandian and B. Raman. 2020, IEEE Access 8, 79440 – 79458.
Got extensive Media coverage > 60 Science Portals
62. A synthetic transcription factor mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus.
Z. Yu, M.Ai, S. Samanta, F. Hashiya, J. Taniguchi, S. Asamitsu, S. Ikeda, K. Hashiya, T. Bando, Ganesh N. Pandian*, L. D. Isaacs* and H. Sugiyama*. 2020, Chem. Commun. 56, 2296-2299, Got extensive Media coverage > 30 Science Portals and Highlighted as Editor's Choice in Asia Research News
61. Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole–imidazole polyamide
M. Malinee, A. Kumar, T. Hidaka, M. Horie, K. Hasegawa, Ganesh N. Pandian* and H. Sugiyama*. 2020, Bioorg. Med. Chem. 28, 115248.
60. Therapeutic gene regulation using pyrrole-imidazole polyamides.
Z. Yu, Ganesh N. Pandian*, T. Hidaka and H. Sugiyama*. 2019, Adv. Drug Deliv. Rev. 147, 66-85 (FRONT COVER).
59. Chemical control system of epigenetics.
T. Vaijayanthi, Ganesh N. Pandian* and H. Sugiyama*. 2018, Chem.Rec. 18, 1-22.
58. Direct observation of H3-H4 octasome by high-speed AFM.
T. Zou, F. Hashiya, Y. Wei, Z. Yu, Ganesh N. Pandian, H Sugiyama. 2018, Chem. Eur. J. 24, 15998-16002.
57. Colloidal stability of lipid/protein-coated nanomaterials in salt and sucrose solutions.
T. Nobeyama, M. Mori, K. Shiyou, Ganesh N. Pandian, H. Sugiyama, T. Murakami. 2018, ChemistrySelect 3, 8325-8331.
56. Biomimetic artificial epigenetic code for targeted acetylation of histones.
J. Taniguchi, Y. Feng#, Ganesh N. Pandian#, F. Hashiya, T. Hidaka, K. Hashiya, S. Park, T. Bando, S. Ito and H. Sugiyama.2018, J. Am. Chem. Soc. 140, 7108-7115. (INSIDE COVER) Got extensive Media coverage > 30 Science Portals and Highlighted as Editor's Choice in Asia Research News
55. Synthetic DNA-binding inhibitor of HES1 alters the Notch signalling pathway and induces neuronal differentiation.
Y. Wei, Ganesh N. Pandian*, Z. Yu, T. Zou, Y. Li, J. Darokar, K. Hashiya, T. Bando, K. Kim and H. Sugiyama*. 2018, ACS Omega. 3, 3608-3616.
54. A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into cardiac mesoderm.
J. Taniguchi, Ganesh N. Pandian, T. Hidaka, K. Hashiya, T. Bando, K. Kim and H. Sugiyama. 2017, Nucleic Acids Res. 45, 9219-9228. Got extensive Media coverage > 20 Science Portals and Highlighted in Asian Scientist.
53. Creation of a synthetic ligand for mitochondrial DNA sequence recognition and promoter-specific transcription suppression.
T. Hidaka, Ganesh N. Pandian,* J. Taniguchi, T. Nobeyama, K. Hashiya, T. Bando and H. Sugiyama*. 2017, J. Am. Chem. Soc. 139, 8444-8447.
(FRONT COVER and JACS SPOTLIGHT ARTICLE) Got extensive Media coverage > 30 Science Portals and Highlighted in ACS Chemical and Engineering News, `Designer molecule silences mitochondrial genes` Volume 95 Issue 30 | p. 7 | Issue Date: July 24, 2017
52. Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitor.
Z. Yu, J. Taniguchi, Y. Wei, Ganesh N. Pandian, K. Hashiya, T. Bando and H. Sugiyama. 2017, Eur. J. Med. Chem. 138, 320-327.
51. Low-temperature carbonization of chicken manure to char and its effect on the growth of Oryza sativa L. Koshihikari and Brassica rapa komatsuna.
T. Ishimori, Y. Takahashi, H. Sato, A. Hassan, Y. Iwamoto, Ganesh N. Pandian and H. Hori. 2017, Euro-Mediterr. J. Environ. Integr. 2, 10. doi:10.1007/s41207-017-0020-2
50. Red fluorescent gut proteins in the mulberry silkworm with immunomodulatory properties.
Ganesh N. Pandian, T. Vaijayanthi and H. Hori. 2016, Trends Entomol. 12, 91-106
49. A multi-target small molecule for targeted transcriptional activation of therapeutically significant nervous system genes.
Y. Wei, Ganesh N. Pandian, T. Zou, J. Taniguchi, S. Sato, G. Kashiwazaki, T. Bando and H. Sugiyama. 2016, ChemistryOpen 5, 517-521.
48. Nature-inspired design of smart biomaterials using the chemical biology of nucleic acids.
Ganesh N. Pandian, H Sugiyama. 2016, Bull. Chem. Soc. J. 89, 843-868. (COVER ARTICLE)
47. Nucleosome assembly alters the accessibility of the antitumor agent duocarmycin B2 to duplex DNA.
T. Zou, S. Kizaki, Ganesh N. Pandian, H Sugiyama. 2016, Chem. Eur. J. 22, 8756-8758.
46. A synthetic DNA-binding domain guides distinct chromatin-modifying small molecules to activate an identical gene network.
L. Han#, Ganesh N. Pandian#, A. Chandran, S. Sato, J. Taniguchi, G. Kashiwazaki, Y. Sawatani, K. Hashiya, T. Bando, Y. Xu, X. Qian and H. Sugiyama. 2015, Angew. Chem. Int. Ed. 54, 8700-8703. #Equal authorship.
45. A synthetic transcriptional activator of genes associated with the retina in human dermal fibroblasts.
J. Syed, A. Chandran, Ganesh N. Pandian, J. Taniguchi, S. Sato, K. Hashiya, G. Kashiwazaki, T. Bando, H Sugiyama. 2015. ChemBioChem 16 (10), 1497-1501.
44. Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells.
S. Patel, T. Pongkulapa, PT, Yin, Ganesh N. Pandian, C. Rathnam, T. Bando, T. Vaijayanthi, H Sugiyama, K-B Lee. 2015. J. Am. Chem. Soc. 137 (14), 4598-4601.
43. Synthetic strategies to identify and regulate noncoding RNAs.
Ganesh N. Pandian, J. Syed, H. Sugiyama. 2015. Long Noncoding RNAs: Structure and Function (23-43).
42. Advancing small-molecule-based chemical biology with next-generation sequencing technologies.
C. Anandhakumar, S. Kizaki, T. Bando, Ganesh N. Pandian, H. Sugiyama. 2015. ChemBioChem 16 (1), 20-38.
41. Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine.
C. Anandhakumar, Y. Li, S. Kizaki, Ganesh N. Pandian, K. Hashiya, T. Bando, H. Sugiyama. 2014. ChemBioChem 15 (18), 2647-2651.
40. Identification of a small molecule that turns `ON` the pluripotency gene circuitry in human fibroblasts.
Ganesh N. Pandian, S. Sato, C. Anandhakumar, J. Taniguchi, K. Takashima, J. Syed, L. Han, A. Saha, T. Bando, H. Nagase, H. Sugiyama. 2014. ACS Chem. Biol. 9 (12), 2729-2736.
39. Targeted Suppression of EVI1 Oncogene Expression by Sequence-Specific Pyrrole-Imidazole Polyamide Mouse Fibroblast.
J. Syed, Ganesh N Pandian, S. Sato, J. Taniguchi, C. Anandhakumar, K. Hashiya, T. Bando and H. Sugiyama. 2014. Chem. Biol. (Cell Press) 21 (10), 1370-1380.
38. Chemically modified synthetic small molecule boosts its biological efficacy against pluripotency genes in mouse fibroblast.
A. Saha, Ganesh N Pandian, S. Sato, J. Taniguchi, Y. Kawamoto, K. Hashiya, T. Bando and H. Sugiyama. 2014. ChemMedChem. 9, 2374-2380.
37. Alteration of epigenetic program to recover memory and alleviate neurodegeneration: Prospects of multi-target molecules. (COVER ARTICLE).
Ganesh N. Pandian, R. D. Taylor, S. Junetha, C. Anandhakumar, A. Saha, T. Vaijayanthi and H. Sugiyama. 2014, Biomater. Sci. 2, 1043-1056.
36. Targeted editing of therapeutic genes using DNA-based transcriptional activators: Scope and challenges.
Ganesh N. Pandian and H. Sugiyama, Book chapter (pp347-365) in Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications ed. by Volker A. Erdmann, Wojciech T. Markiewicz, and Jan Barciszewski.
35. Cellular reprogramming for pancreatic beta cell regeneration: clinical potential of small molecule control.
Ganesh N. Pandian, J. Taniguchi, and H. Sugiyama. 2014, Clin. Transl. Med., 3, 6.
34. Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts.
Ganesh N. Pandian, J. Taniguchi, S. Junetha, S. Sato, C. Anandhakumar, A. Saha, T. Bando, H. Nagase, and H. Sugiyama. 2014, Sci. Rep. (Nature Publishing Group). 4, e3843.
33. A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell (Selected as a HOT PAPER).
L. Han#, Ganesh N. Pandian#, S. Junetha, S. Sato, C. Anandhakumar, J. Taniguchi, A. Saha, T. Bando, H. Nagase, and H. Sugiyama. 2013, Angew. Chem. Int. Ed. 52, 13410-13413. #Equal authorship.
32. Clinical-Grade iPS Cells: Need For versatile small molecules and optimal cell sources.
Y -L. Wu#, Ganesh N. Pandian#, Y-P. Ding, W. Zhang, Y. Tanaka and H. Sugiyama, 2013, Chem. Biol. (Cell Press, Featured Review) 20, 1311-1322. #Equal authorship.
31. Chemically induced pluripotent stem cells (CiPSCs): A transgene-free approach.
S. Masuda, J. Wu, T. Hishida, Ganesh N. Pandian, H. Sugiyama, J. C. Belmonte, 2013, J. Mol. Cell Biol. 5, 354-355.
30. Design of a new fluorescent probe: Pyrrole/Imidazole hairpin polyamides with pyrene conjugation at their γ-turn.
T. Vaijayanthi, T. Bando, K. Hashiya, Ganesh N. Pandian and H, Sugiyama. 2013, Bioorg. Med. Chem. 21, 852-855.
29. Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity.
A. Saha, Ganesh N. Pandian, S. Sato, J. Taniguchi, K. Hashiya, T. Bando and H, Sugiyama. 2013, Bioorg. Med. Chem. 21, 4201-4209.
28. Strategies to modulate heritable epigenetic defects in cellular machinery: Lessons from nature.
Ganesh N. Pandian and H.Sugiyama. 2013, Pharmaceuticals, 6, 1-24.
27. A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblast.
Ganesh N. Pandian, Y. Nakano, S. Sato, H. Morinaga, T. Bando, H. Nagase and H. Sugiyama. 2012, Sci. Rep. (Nature Publishing Group). 2, e544. (Highlighted article in Stem Cell Journal). http://www.stemcellsportal.com/news-and-press/latest-news/481-targeting-small-molecules-hits-the-spot-for-reprogramming-.html
26. Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugate as sequence-selective DNA probes.
T. Vaijayanthi, T. Bando, Ganesh N. Pandian and H. Sugiyama. 2012, ChemBioChem. 13, 2170-2185.
25. Synthesis and biological properties of highly sequence-specific-alkylating N-Methylpyrrole–N-Methylimidazole polyamide conjugates.
G. Kashiwazaki, T. Bando, T. Yoshidome, S. Masui, T. Takagaki, K. Hashiya, Ganesh N. Pandian, J. Yasuoka, K. Akiyoshi and H. Sugiyama. 2012, J. Med. Chem. 55, 2057-2066.
24. Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes.
Ganesh N. Pandian, A. Ohtsuki, T. Bando, S. Sato, K. Hashiya, H. Sugiyama, 2012, Bioorg. Med. Chem. 20, 2656-2660.
23. Programmable genetic switches to control transcriptional machinery of pluripotency.
Ganesh N. Pandian and H. Sugiyama. 2012, Biotechnol. J. 7, 798-809.
22. Synthetic small molecules for epigenetic activation of pluripotent genes in mouse embryonic fibroblasts.
Ganesh N. Pandian, K. Shinohara, A. Ohtsuki, Y. Nakano, Y. Yamada, A. Watanabe, N. Terada, S. Sato, H. Morinaga and H. Sugiyama. 2011, ChemBioChem. 12 (18), 2822-2828.
21. Depletion of 14-3-3 protein exacerbates cardiac oxidative stress, inflammation and remodeling process via modulation of MAPK/NF-ĸB signaling pathways after streptozotocin-induced Diabetes mellitus.
R. A Thandavarayan, V. V Giridharan, F. R. Sari, S. Arumugam, P.T. Veeraveedu, Ganesh N Pandian, S. S Palaniyandi, M. Ma, K. Suzuki, N. Guruswamy and K. Watanabe. 2011, Cell. Physiol. Biochem. 28(5), 911-922.
20. Midgut juice of Bacillus thuringiensis Cry1Ac resistant Plutella xylostella contains a three‐fold amount of Glucosinolate Sulfatase than the susceptible strain.
T. Yamazaki, T. Ishikawa, Ganesh N. Pandian, K. Okazaki, Y. Tachikawa, T. Mitsui, C. Angusthanasombat and H. Hori. 2011, Pest. Biochem. Physiol. 101, 125-131.
19. Formation of macromolecule complex with Bacillus thuringiensis Cry1A toxins and chlorophyllide-binding 252-kDa lipocalin like protein locating on Bombyx mori midgut membrane.
Ganesh N. Pandian, T. Ishikawa, T. Vaijayanthi, D. M. Hossain, S. Yamamoto, T. Nishiumi, C. Angusthanasombat and H. Hori. 2010,
J. Membr. Biol. 237(2-3), 125-136.
18. Investigation of physicochemical condition to stabilize phosphatidylcholine-liposome enclosing fluorescent calcein and its exploitation for analysis of pore formation with Cry1A toxins of Bacillus thuringiensis.
K. Haginoya, V. Thangavel, Ganesh N. Pandian, K. Tomimoto, Y. Shitomi, C. Angsuthanasombat and H. Hori. 2010, Appl. Entomol. Zool. 45 (3), 477–488.
17. Novel applications of silicon and porous silicon based EISCAP biosensors.
A. Mathew, Ganesh Pandian, A. Chadha, E. Bhattacharya. 2009, Phys. Status Solidi A, 206, 1369-1373.
16. Bombyx mori midgut membrane protein P252, which binds to Bacillus thuringiensis Cry1A, is a chlorophyllide-binding protein, and their resulting complex has antimicrobial activity.
Ganesh N. Pandian, T. Ishikawa, M. Togashi, Y. Shitomi, K. Haginoya, S. Yamamoto, T. Nishiumi and H. Hori. 2008, Appl. Environ. Microbiol. 74 (5), 1324-1331.
15. Deracemisation of beta-hydroxy esters using immobilized whole cells of Candida parapsilosis ATCC 7330: substrate specificity and mechanistic investigation.
S.K.Padhi, D. Titu, N. Ganesh Pandian and A. Chadha. 2006, Tetrahedron 62, 5133-5140.
14. Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330: Effect of substrate structure and mechanism.
B. Baskar, N. Ganesh Pandian, K. Priya, and A. Chadha. 2005, Tetrahedron 61, 12296-12306.
13. Biocatalytic deracemization: An efficient and simple strategy for preparation of chiral α- and β-hydroxy esters.
B. Baskar, S. K. Padhi, N. Ganesh Pandian, T. Vaijayanthi and A. Chadha. 2005. Chem. Res. Chinese U. 21, 46.
12. Microbial deracemisation of aromatic β-hydroxy acid esters.
S. K. Padhi, N. Ganesh Pandian and A. Chadha. 2004, J. Mol. Catal. B. Enzymatic. 29, 25-29.
11. Asymmetric reduction of alkyl 2-oxo-4-arylbutanoates and -but-3-enoates by Candida parapsilosis ATCC 7330: assignment of the absolute configuration of ethyl 2-hydroxy-4-(p-methylphenyl) but-3-enoate by 1H NMR.
S. K. Padhi, N. Ganesh Pandian and A. Chadha. 2004, Tetrahedron: Asymmetry. 15, 3961-3966.
Conference Proceedings
10. Differentially Expressed MicroRNAs During Early Endochondral Differentiation Of Human Mesenchymal Stromal Cells As Biomarkers For Non-union Fractures.
Franziska L. Breulmann; Soundhar Ramasamy; Manuel Herzog; Ganesh N. Pandian; Elena Della Bella; Martin J. Stoddart. 2023, ORS https://ors-org.s3.amazonaws.com/wp-content/uploads/2023/02/Index-and-Posters.pdf
9. Programmable synthetic molecular codes for bioengineering.
Ganesh N. Pandian. 2018, 한국생물공학회 학술대회, 31.
杉山, 弘; 板東, 俊和; Ganesh, N Pandian; 佐藤, 慎祐; 谷口, 純一; Tingting, Zou; Yulei, Wei. 京都大学アカデミックデイ2015 : ポスター/展示 (2015)
7. Characterization of a Cry1A and chlorophyllide-binding 252-kDa protein and its antimicrobial and physiological applications. Ganesh N. Pandian, T. Ishikawa, Y. Shitomi, M. Togashi, T. Katagiri, K. Haginoya, and H. Hori. 2007, Proc. of International conference on Bacillus thuringiensis 1, 54-60.
6. Sensitive Silicon and Porous Silicon Triglyceride Biosensors.A. Mathew, N. Ganesh Pandian, A. Chadha and E. Bhattacharya, 2005, Proc. of Intl. Workshop on Physics of Semiconductor Devices 1, 562-564.
5. Optimization of porous silicon based EISCAP structures for triglyceride sensors. A. Mathew, Ganesh N. Pandian, A. Chadha and E. Bhattacharya. 2005, Proc. of Intl. Workshop on Physics of Semiconductor Devices. C-10, 20-22.
4. Preparation of chiral synthons: Biocatalytic deracemisation of aryl α-hydroxy esters.B. Baskar, Ganesh N. Pandian K. Priya and A. Chadha. 2005. Advanced Biotech, 111(7), 12.
3. Synthesis of optically pure α-hydroxy esters: A biocatalytic approach.S.K. Padhi, N. Ganesh Pandian and A. Chadha. 2005. Advanced Biotech, 111(7), 16.
2. Screening, characterization and application of an indigenous lipase.K. Priya, N. Ganesh Pandian and A. Chadha. 2005, Advanced Biotech. 111 (7), 16.
1. Microbial deracemisation of β-hydroxy acid esters-An important strategy towards various chiral intermediates.S. K. Padhi, N. Ganesh Pandian and A. Chadha. 2003, Chem. Listy 97, 479-480.